Vaccines to Prevent Rotavirus: RV(Rotavirus vaccine)

Rotavirus is a virus that causes diarrhea, mostly in babies and young children which can lead to dehydration. Vomiting and fever are also common in babies with rotavirus.

Updated: June 16, 2022

It is important that children, especially infants and young children, receive recommended immunizations on time. Vaccines also protect teenagers and adults to keep them healthy throughout their lives.
Rotavirus is a virus that causes diarrhea, mostly in babies and young children which can lead to dehydration. Vomiting and fever are also common in babies with rotavirus. Rotavirus causes acute gastroenteritis which is inflammation of the stomach and intestines. Adults and older children can also become infected with rotavirus. They will usually have milder symptoms than infants and young children.

Rotavirus Vaccine:

There are two brands of rotavirus vaccine available. Depending on which vaccine is used your baby will get either 2 or 3 doses. The first Dose is recommended at the age of 2 months. Second dose at the age of 4 months and third one at the age of 6 months if required.
Your child must get the first dose of rotavirus vaccine before 15 weeks of age, and the last by age 8 months. Rotavirus vaccine may safely be given at the same time as other vaccines.
Almost all babies who get rotavirus vaccine will be protected from severe rotavirus diarrhea. And most of these babies will not get rotavirus diarrhea at all. The vaccine will not prevent diarrhea or vomiting caused by other germs.

Things and condition taken to be consideration before getting the vaccine:

  • If the baby has had a life-threatening allergic reaction to a dose of rotavirus vaccine should not get another dose. A baby who has a severe allergy to any part of rotavirus vaccine should not get the vaccine. Speak to your doctor if your baby has any severe allergies that you are aware of, including a severe allergy to latex.
  • Babies with severe combined immunodeficiency (SCID) should not get rotavirus vaccine.
  • Babies who have had a type of bowel blockage called intussusception should not get rotavirus vaccine.
  • Babies who are mildly ill can get the vaccine. Babies who are moderately or severely ill should wait until they recover. This includes babies with moderate or severe diarrhea or vomiting.
Check with your doctor if the immune system of your baby is weakened because of:
  •     HIV/AIDS or any other disease that affects the immune system
  •     treatment with drugs such as steroids
  •     cancer or cancer treatment with x-rays or drugs

Risks of RV vaccine:

There are chances of side effects are usually mild and go away on their own. Serious reactions are also possible but are rare. Some of the mild Problems following RV vaccine include:
Babies might become irritable, or have mild, temporary diarrhea or vomiting after getting a dose of rotavirus vaccine.
There is a small risk of intussusception from rotavirus vaccination which usually occurs within a week after the first or second dose of the vaccine.

Problems that could happen after any vaccine:

Any medication can cause a severe allergic reaction. Such reactions from a vaccine are very rare and usually happen within a few minutes to a few hours after the vaccination.
As with any medicine, there is a very remote chance of a vaccine causing a serious injury or death. The safety of vaccines is always being monitored. For more information, visit the Vaccine Safety site.

Look for any serious problem:

  • Look for signs of stomach pain along with severe crying for intussusception. These episodes could last just a few minutes and come and go several times in an hour. Babies might pull their legs up to their chest.
  • Your baby might also vomit several times or have blood in the stool, or could appear weak or very irritable. These signs would usually happen during the first week after the first or second dose of rotavirus vaccine, but look for them any time after vaccination.
  • Also look for anything else that concerns you, such as signs of a severe allergic reaction, very high fever or unusual behavior.
  • Signs of a severe allergic reaction can include hives, swelling of the face and throat, difficulty breathing, or unusual sleepiness. These would usually start a few minutes to a few hours after the vaccination.

What should be done?

If you think it is intussusception, call a doctor right away. Take your baby to a hospital if you can not reach your doctor and tell them when your baby got the rotavirus vaccine.
If you think it is a severe allergic reaction or other emergency that can not wait, call 9-1-1 or get your baby to the nearest hospital.
The reaction should be reported to the Vaccine Adverse Event Reporting System (VAERS) through the VAERS website or by calling 1-800-822-7967. VAERS is only for reporting reactions. They do not give medical advice.
If you are injured by a vaccine, you can file a claim in  National Vaccine Injury Compensation Program (VICP) by calling 1-800-338-2382 or visiting the VICP website to get the compensation.

Learn more about Vaccine:

Your doctor can give you the vaccine package insert or suggest other sources of information.
You can call your local or state health department or can contact the Centers for Disease Control and Prevention (CDC) by:
        Calling 1-800-232-4636 (1-800-CDC-INFO)
        Visiting  CDC vaccines website







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